Derek P Narendra Selected Research

Parkinson Disease (Parkinson's Disease)

1/2023	CHCHD2 and CHCHD10-related neurodegeneration: molecular pathogenesis and the path to precision therapy.
1/2022	Heterozygous PRKN mutations are common but do not increase the risk of Parkinson's disease.
11/2021	Mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC.
10/2021	α-Synuclein Deposition in Sympathetic Nerve Fibers in Genetic Forms of Parkinson's Disease.
1/2021	Mitochondrial Dysfunction and Mitophagy in Parkinson's Disease: From Mechanism to Therapy.
11/2018	CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.
1/2018	Parkin and PINK1 mitigate STING-induced inflammation.
5/2011	Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control.
1/2011	Mechanisms of mitophagy.
12/2010	Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.

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Derek P Narendra Research Topics

Disease

11	Parkinson Disease (Parkinson's Disease) 01/2023 - 11/2010
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2023 - 11/2018
3	Parkinsonian Disorders (Parkinsonism) 07/2013 - 06/2010
2	Mitochondrial Myopathies (Mitochondrial Myopathy) 10/2023 - 01/2022
2	Frontotemporal Dementia (Semantic Dementia) 10/2023 - 11/2018
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 01/2021
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 10/2023
1	Cardiomyopathies (Cardiomyopathy) 10/2023
1	Iron Deficiencies 06/2023
1	Muscular Diseases (Myopathy) 01/2022
1	Neuroinflammatory Diseases 01/2022
1	Bites and Stings (Sting) 01/2018
1	Inflammation (Inflammations) 01/2018

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 10/2023 - 01/2011
4	Mitochondrial Proteins (Mitochondrial Protein)IBA 06/2023 - 11/2018
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 01/2018
2	PTEN-induced putative kinaseIBA 05/2011 - 01/2011
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 12/2010 - 06/2010
1	Phosphates (Orthophosphate)IBA 11/2021
1	quinoline-val-asp(OMe)-CH2-OPHIBA 11/2021
1	DeferiproneIBA 11/2021
1	Isoflurophate (DFP)FDA Link 11/2021
1	OligomycinsIBA 11/2021
1	antimycinIBA 11/2021
1	Bovine Serum AlbuminIBA 11/2021
1	UbiquitinIBA 11/2021
1	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2021
1	SynucleinsIBA 10/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2018
1	CytokinesIBA 01/2018
1	Interferon Type IIBA 01/2018
1	Serine (L-Serine)FDA Link 07/2013
1	Phosphotransferases (Kinase)IBA 11/2010

Therapy/Procedure

2	Therapeutics 01/2022 - 01/2021